Take these drugs, the sun can't!

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Do you know? The sun can't be basked in if you want to, so be careful after taking these drugs.

Do you know? The sun can't be basked in if you want to, so be careful after taking these drugs.


Proper exposure to the sun can enhance the body's resistance and prevent physical and mental diseases, but if you are taking the following drugs, you may need to avoid the sun.


List of commonly used drugs that are easy to induce photosensitivity



Antibacterial drugs

Sparfloxacin, fleroxacin, norfloxacin, ofloxacin, levofloxacin, ciprofloxacin, clinfloxacin, lomefloxacin, sitafloxacin, trimethoprim, minocycline, doxycycline, demecycline, gentamicin, pyrazinamide, griseofulvin, ketoconazole, flucytosine, itraconazole, voriconazole, terbinafine

antineoplastic agents

Methotrexate, vincristine, hydroxyurea, fluorouracil, sorafenib, vemurafenib, flunamide, docetaxel, capecitabine, doxorubicin, tegafur, paclitaxel, dacarbazine, epirubicin

Non-steroidal anti-inflammatory drugs

Aspirin, diclofenac, ibuprofen, ketoprofen, rofecoxib, meloxicam, butaproxone, naproxen, piroxicam, nabumetone, indomethacin, etc


Hydrochlorothiazide (double gram), furosemide (furosemide), indapamide, aminopterene

anti-allergy drug

Chlorpheniramine maleate (chlorpheniramine), diphenhydramine, cyproheptadine, sodium cromolyn, cetirizine, loratadine, promethazine

hypoglycemic drug

Glimepiride, Glipizide, Glibenclamide, Metformin, Chlorsulfopropamide, Tolbutamide, Sitagliptin

lipid-lowering drug

Gemfirozil, bezafibrate, fenofibrate, simvastatin, pravastatin, fluvastatin, atorvastatin

antihypertensive drug

CCB: nifedipine, nimodipine, nitrendipine, felodipine, amlodipine, diltiazem

ACEI: Benazepril, Captopril, Enalapril, Lisinopril, Ramipril, Quinapril

ARB: Losartan, Valsartan

Class β-RB: Tloriprolol

Acid Inhibitor

Ranitidine, omeprazole, pantoprazole, rabeprazole

Antiarrhythmic drugs

Amiodarone, quinidine, propranolol (propranolol)

anti-malarial drugs

Quinine, chloroquine, hydroxychloroquine, pyrimethamine

Nervous system drugs

Alprazolam, Lamotrigine, Thioridazine, Flupenthixol, Olanzapine, Clozapine, Chlorpromazine, Perphenazine, Fluphenazine, Trifluoperazine, Imipramine, Desipramine, Doxepine, Amitriptyline, Sulazepam, Fluoxetine (Prozac), Paroxetine, Fluvoxamine, Sertraline, Venlafaxine

External use

Compound hydroquinone cream, isovitamin A acid cream


After taking these drugs in the sun, may cause photosensitive reaction. Photosensitivity refers to adverse reactions caused by exposure to sunlight (mainly ultraviolet UVA and UVB) after taking or topical use of certain drugs. According to the occurrence mechanism, it can be divided into phototoxic reaction (mainly occurs in the system drug) and photoallergic reaction (induced by local and systemic drug).


Phototoxic reaction: clinical manifestations similar to solar dermatitis, for the edema of erythema, severe blisters, conscious burning and tingling.


Light allergy: clinical manifestations of eczema-like view, visible erythema, papules, blisters or exudation, generally do not leave pigmentation, chronic damage can make skin hypertrophy or lichenification, some may develop into chronic, persistent light sensitivity reaction.


Special reminder: Chinese medicine can also cause photosensitive reactions, such as Psoralea, Forsythia, Bamboo Yellow, Duhuo, Radix, Radix, Radix, Radix Angelicae dahuricae, Radix, Herba Daixianpi, Herba Agrimoniae, Peucedanum, Herba Sopranoides, Schizonepeta, etc.


In addition, there are these diseases in the sun should also be careful: those with bleeding diseases, serious heart disease, uremia, active tuberculosis and other serious diseases should not be exposed to the sun.


In addition, too strong solar radiation can easily cause cataracts, photodermatitis, conjunctivitis and thermal regulation disorders, and prevention should be particularly strengthened. For children with rickets symptoms or who have never taken cod liver oil and calcium tablets, especially malnourished or artificially fed children, vitamin D preparations should be taken for a period of time to prevent sudden convultion in the sun.